PIK3C2A Mouse anti-Human, Clone: OTI3H2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF801692

Catalog No. 50-166-5690

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to omolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Specifications

• Antigen: PIK3C2A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PIK3C2A
• Gene Alias: CPK, PI3-K-C2(ALPHA), PI3-K-C2A, PI3K-C2-alpha, PI3K-C2alpha
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5286
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3H2
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O00443
• Gene Symbols: PIK3C2A
• Immunogen: Human recombit protein fragment corresponding to amino acids 230-560 of human PIK3C2A produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1