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Invitrogen™ PIK3C2B Polyclonal Antibody
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Catalog No. PIPA5100895
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PIPA5100895 100 μL
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Catalog No. PIPA5100895 Supplier Invitrogen™ Supplier No. PA5100895
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PIK3C2B.

The Class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the class I PI3 kinases, the class II enyzmes have been linked to diverse, receptor-mediated cellular processes including insulin signaling, neuronal survival, and growth factor signaling. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIK3C2B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PIK3C2B
Gene Accession No. O00750
Gene Alias C2-PI3K; C330011J12Rik; Gm199; phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; phosphoinositide 3-kinase-C2-beta; phosphoinositide-3-kinase, class 2, beta polypeptide; pi3kc2b; PI3KC2beta; PI3K-C2beta; PI3K-C2-beta; PIK3C2B; PTDINS-3-kinase C2 beta; ptdIns-3-kinase C2 subunit beta
Gene Symbols PIK3C2B
Host Species Rabbit
Immunogen A synthesized peptide derived from human PIK3C2B(Accession O00750), corresponding to amino acid residues F790-W840.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 240752, 5287
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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