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Invitrogen™ PIK3C2G Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA515239
Description
PIK3C2G Polyclonal Antibody for Western Blot, IHC (P)
PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.
Specifications
PIK3C2G | |
Polyclonal | |
Unconjugated | |
PIK3C2G | |
C80387; phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma; phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI 3-kinase C2gamma; PI3KC2gamma; PI3K-C2gamma; PI3K-C2-gamma; Pik3c2g; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma | |
Rabbit | |
Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
RUO | |
5288 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
O75747 | |
PIK3C2G | |
KLH conjugated synthetic peptide between 93-123 amino acids from the N-terminal region of human PI3KC2G. | |
400 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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