Invitrogen™ PIK3CB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120062

Catalog No. PIPA5120062

Description

Positive test controls include: MCF7, Mouse brain. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: KVKTKKSTKT INPSKYQTIR KAGKVHYPVA WVNTMVFDFK GQLRTGDIIL HSWSSFPDEL EEMLNPMGTV QTNPYTENAT ALHVKFPENK KQPYYYPPFD KIIEKAAEIA SSDSANVSSR GGKKFLPVLK EILDRDPLSQ LCENEMDLIW TLRQDCREIF PQSLPKLLLS IKWNKLEDVA QLQALLQIWP K.

PIK3CB (phosphatyidylinositol 4,5-biphosphate 3-kinase catalyic subunit beta isoform) is a phosphoinositide-3-kinase that phosphorylates PtdIns (phosphatidylinositol), PtdIns4P (phosphatidylinositol 4-phosphate), and PtdIns(4,5)P2 (phosphatidylinositol 4,5-biphosphate) to generate phosphatidylinositol 3,4,5-triphosphate (PIP3). PIP3 plays a key role in recruiting PH domain-containing proteins to the membrane and activating signaling cascades involved in cell growth, survival, proliferation, motility, and morphology.

Specifications

• Antigen: PIK3CB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PIK3CB
• Gene Alias: 1110001J02Rik; AI447572; catalytic phosphatidylinositol 3-kinase beta; p110beta; phosphatidylinositol 3-kinase catalytic subunit beta isoform; phosphatidylinositol 3-kinase, catalytic subunit, beta isoform; phosphatidylinositol 3-kinase, catalytic, beta polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; phosphoinositide-3-kinase, catalytic, beta polypeptide; PI3K; PI3Kbeta; PI3K-beta; pi3kcb; PI3-kinase p110 subunit beta; PI3-kinase subunit beta; PIK3C1; Pik3cb; PtdIns-3-kinase p110; ptdIns-3-kinase subunit beta; ptdIns-3-kinase subunit p110-beta
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5291, 74769, 85243
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.69 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P42338, Q8BTI9, Q9Z1L0
• Gene Symbols: PIK3CB
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 410-600 of human PI3 Kinase p110 beta (NP_0062101).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG