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PIKE Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501567270
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50-156-7270 100 μL
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Catalog No. 50-156-7270 Supplier Bethyl Laboratories, Inc Supplier No. A304262A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

AGAP2 (also known as PIKE-A), a putative oncogene, shows elevated expression in cancer cells compared to non-transformed cells and has been implicated as regulators of cancer cell invasion into normal tissues. A contributor to brain, eye, breast and liver cancers, AGAP2 belongs to the centaurin gamma-like family with two ANK repeats, an Arf-GAP domain, a Miro domain and a PH domain is a GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. The Arf-GAP domain interacts with G domain and may regulate its GTPase activity. GAP activity of AGAP2 is stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and, to a lesser extent, by phosphatidylinositol 3,4,5-trisphosphate (PIP3). Phosphatidic acid potentiates PIP2 stimulation. Several isoforms of AGAP2 have been reported.

Specifications

Antigen PIKE
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene AGAP2
Gene Accession No. Q99490
Gene Alias CENTG1; centaurin, gamma 1; AGAP2; FLJ16430; GGAP2; KIAA0167; PIKE; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; GTP-binding and GTPase activating protein 2; centaurin gamma1; phosphoinositide 3-kinase enhancer
Gene Symbols AGAP2
Host Species Rabbit
Immunogen Between 450 and 500
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116986
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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