PIKFYVE Monoclonal Antibody (OTI1D3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810373

Catalog No. 50-168-3358

Description

PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva.

Specifications

• Antigen: PIKFYVE
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9Y2I7
• Gene Symbols: PIKFYVE
• Immunogen: Full length human recombit protein of human PIKFYVE produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1D3
• Conjugate: Unconjugated
• Gene: PIKFYVE
• Gene Alias: CFD, FAB1, HEL37, PIP5K, PIP5K3, ZFYVE29
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 200576
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid