Invitrogen™ PIKFYVE Polyclonal Antibody

Catalog No.	Quantity
PIPA575977	100 μL

Catalog No. PIPA575977 Supplier Invitrogen™ Supplier No. PA575977

Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva.

Specifications

• Antigen: PIKFYVE
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene: PIKFYVE
• Gene Accession No.: Q9Y2I7, Q9Z1T6
• Gene Alias: 1-phosphatidylinositol 3-phosphate 5-kinase; 1-phosphatidylinositol-3-phosphate 5-kinase; 5230400C17Rik; CFD; epididymis luminal protein 37; FAB1; FYVE finger-containing phosphoinositide kinase; HEL37; Kiaa0981; p235; Phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III; phosphatidylinositol-4-phosphate 5-kinase, type III; phosphoinositide kinase, FYVE finger containing; phosphoinositide kinase, FYVE-type zinc finger containing; PIKfyve; Pip5k; PIP5K3; Pipk5k3; PipkIII; PIPkin-III; PtdIns(4)P-5-kinase; type III PIP kinase; ZFYVE29; zinc finger, FYVE domain containing 29
• Gene Symbols: PIKFYVE
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to amino acids 72-116 of Human PIKFYVE.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18711, 200576, 316457
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG