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Invitrogen™ PIKFYVE Polyclonal Antibody
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Catalog No. PIPA5103242
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PIPA5103242 100 μL
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Catalog No. PIPA5103242 Supplier Invitrogen™ Supplier No. PA5103242
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PIP5K.

PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIKFYVE
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PIKFYVE
Gene Accession No. Q9Y2I7, Q9Z1T6
Gene Alias 1-phosphatidylinositol 3-phosphate 5-kinase; 1-phosphatidylinositol-3-phosphate 5-kinase; 5230400C17Rik; CFD; epididymis luminal protein 37; FAB1; FYVE finger-containing phosphoinositide kinase; HEL37; Kiaa0981; p235; Phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III; phosphatidylinositol-4-phosphate 5-kinase, type III; phosphoinositide kinase, FYVE finger containing; phosphoinositide kinase, FYVE-type zinc finger containing; PIKfyve; Pip5k; PIP5K3; Pipk5k3; PipkIII; PIPkin-III; PtdIns(4)P-5-kinase; type III PIP kinase; ZFYVE29; zinc finger, FYVE domain containing 29
Gene Symbols PIKFYVE
Host Species Rabbit
Immunogen A synthesized peptide derived from human PIKFYVE(Accession Q9Y2I7), corresponding to amino acid residues T283-N333.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18711, 200576
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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