PILRA Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7479	150 μL

Catalog No. 50-172-7479 Supplier Proteintech Group Inc Supplier No. 118181AP150UL

Description

Rabbit Polyclonal Antibody

The other band of about 61 kDa detected by this antibody may present a heavily glycosylated form of PILRalpha.

SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILR beta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILR alpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.

Specifications

• Antigen: PILRA
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.18 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PILRA
• Gene Accession No.: Q9UKJ1
• Gene Alias: Cell surface receptor FDF03, FDF03, Inhibitory receptor PILR alpha, PILRA
• Gene Symbols: PILRA
• Host Species: Rabbit
• Immunogen: PILRA Fusion Protein Ag2385
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 29992
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG