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Invitrogen™ PIM1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA589681
Description
Positive Samples: H460, Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Cytoplasm, Nucleus Immunogen sequence: MPHEPHEPLT PPFSALPDPA GAPSRRQSRQ RPQLSSDSPS AFRASRSHSR NATRSHSHSH SPRHSLRHSP GSGSCGSSSG HRPCADILEV GMLLSKINSL AHLRAAPCND LHATKLAPGK EKEPLESQYQ VGPLLGSGGF GSVYSGIRVS DNLPVAIKHV EKDRISDWGE LPNGTRVPME VVLLKKVSSG FSGVIRLLDW FERPDSFVLI LERPEPVQDL FDFITERGAL QEELARSFFW QVLEAVRHCH NCGVLHRDIK DENILIDLNR GELKLIDFGS GALLKDTVYT DFDGTRVYSP PEWIRYHRYH GRS.
The proto-oncogene PIM1 is upregulated in prostate cancer. PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
Specifications
PIM1 | |
Polyclonal | |
Unconjugated | |
PIM1 | |
non-specific serine/threonine protein kinase; Oncogene PIM1; PIM; Pim1; Pim-1; pim-1 kinase 44 kDa isoform; pim-1 oncogene; pim-1 oncogene (proviral integration site 1); Pim-1 proto-oncogene, serine/threonine kinase; proto-oncogene serine/threonine-protein kinase Pim-1; proviral integration site 1; serine/threonine-protein kinase pim-1; serine-threonine kinase PIM-1 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
18712, 24649, 5292 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot | |
0.7 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
P06803, P11309, P26794 | |
PIM1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human PIM1 (NP_0012301151). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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