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Pim2 Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™
SDP

Catalog No. 501993764
Encompass
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50-199-3764 10 μg
50-199-3763 100 μg
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Catalog No. 50-199-3764 Supplier Active Motif Supplier No. 91240
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Mouse Recombinant Monoclonal Antibody

PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.

Specifications

Antigen Pim2
Applications Western Blot
Classification Monoclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene PIM2
Gene Accession No. Q9P1W9
Gene Alias DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; Pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; Serine/threonine-protein kinase pim-2
Gene Symbols PIM2
Host Species Mouse
Immunogen This antibody was raised against a recombinant protein corresponding to human PIM2 (pim-2 oncogene).
Purification Method Protein A
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11040
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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