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Invitrogen™ PIM2 Recombinant Rabbit Monoclonal Antibody (3V1S5)
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Catalog No. PIMA542916
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100 μL
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PIMA542916 100 μL
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Catalog No. PIMA542916 Supplier Invitrogen™ Supplier No. MA542916
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HepG2, K-562, Raji. Immunogen sequence: PAPPGTPTPP PGGKDREAFE AEYRLGPLLG KGGFGTVFAG HRLTDRLQVA IKVIPRNRVL GWSPLSDSVT CPLEVALLWK VGAGGGHPGV IRLLDWFETQ EGFMLVLERP L.

PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIM2
Applications ELISA, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 3V1S5
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PIM2
Gene Accession No. Q62070, Q9P1W9
Gene Alias DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2
Gene Symbols PIM2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 10-120 of human PIM2 (NP_0068662).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11040, 18715, 317366
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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