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Invitrogen™ PIMT Polyclonal Antibody
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Catalog No. PIPA543252
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100 μL
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PIPA543252 100 μL
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Catalog No. PIPA543252 Supplier Invitrogen™ Supplier No. PA543252
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Description

Rabbit Polyclonal Antibody

Peptide sequence: IDENPASDFD DSGSLLGFKY GSGQKYGGIP NFSHRQVRYL EKNVKLKSKY Sequence homology: Cow: 92%; Dog: 92%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93%.

Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIMT
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TGS1
Gene Accession No. Q96RS0
Gene Alias Cap-specific guanine-N2 methyltransferase; CLL-associated antigen KW-2; D4Ertd800e; HCA137; Hepatocellular carcinoma-associated antigen 137; LOW QUALITY PROTEIN: trimethylguanosine synthase; NCOA6IP; nuclear receptor coactivator 6 interacting protein; nuclear receptor coactivator 6-interacting protein; Pimt; PIPMT; PRIP-interacting protein with methyltransferase motif; TGS1; tgs1 {ECO:0000250; Trimethylguanosine synthase; trimethylguanosine synthase 1; trimethylguanosine synthase homolog; trimethylguanosine synthase homolog (S. cerevisiae); trimethylguanosine synthase-like protein; UniProtKB:Q96RS0}
Gene Symbols TGS1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human TGS1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 96764
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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