PINK1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-4035	Proteintech Group Inc 232741AP150UL	150 μL

Description

PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes. The kinase domain of PINK1 appears to be critical in its protective effects. Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress. Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes. When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson′s disease are triggered.

Specifications

• Antigen: PINK1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q99MQ3, Q9BXM7
• Gene ID (Entrez): 65018, 68943
• Immunogen: PINK1 Fusion Protein Ag19825
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PINK1

• Concentration: 0.2 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: BRPK, PARK6, PINK1, PTEN induced putative kinase 1
• Gene Symbols: PINK1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody