PIp1 Mouse anti-Human, Clone: 4E7, Bioss

Catalog No.	Quantity
50-197-9831	100 μL

Catalog No. 50-197-9831 Supplier Bioss Supplier No. BSM51197M

Description

Mouse Monoclonal Antibody

PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5′ UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5′ UTRs, have been identified for this gene.

Specifications

• Antigen: PIp1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 4E7
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene: PLP1
• Gene Accession No.: P60201
• Gene Alias: BOS_25620; DM20; GPM6C; HLD1; jimpy; jp; Lipophilin; major myelin proteolipid protein; MMPL; msd; Myelin proteolipid protein; myelin synthesis deficiency; PLP; PLP/DM20; PLP1; PMD; proteolipid protein (myelin) 1; Proteolipid protein (Pelizaeus-Merzbacher disease spastic paraplegia 2 uncomplicated); Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); proteolipid protein 1; proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated); rsh; rump shaker; SPG2
• Gene Symbols: PLP1
• Host Species: Mouse
• Immunogen: KLH conjugated synthetic peptide between 248-277 amino acids from the central region of rat PIp1.
• Purification Method: Size-exclusion - Dialysis
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5354
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM