Invitrogen™ LILRB3 Monoclonal Antibody (326414)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA524049

Catalog No. PIMA524049

Description

In Western blots, this antibody does not cross-react with recombinant mouse PIR-A. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: LILRB3
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P97484
• Gene Symbols: LILRB3
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse PIR-B Gly24-Gly635.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Western Blot
• Clone: 326414
• Conjugate: Unconjugated
• Gene: LILRB3
• Gene Alias: CD85 antigen-like family member A; CD85A; Cell-surface glycoprotein p91; Gp91; HL9; ILT5; ILT-5; immunoglobulin-like transcript 5; leucocyte Ig-like receptor B3; leukocyte immunoglobulin like receptor B3; leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; LILRA6; Lilrb3; LIR3; LIR-3; monocyte inhibitory receptor HL9; paired Ig-like receptor B; paired immunoglobulin-like receptor B; PIRB; PIR-B
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 18733
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized