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Invitrogen™ LILRB3 Monoclonal Antibody (326414)
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Catalog No. PIMA524049
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100 μg
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Catalog No. Quantity
PIMA524049 100 μg
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Catalog No. PIMA524049 Supplier Invitrogen™ Supplier No. MA524049
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Description

Rat Monoclonal Antibody

In Western blots, this antibody does not cross-react with recombinant mouse PIR-A. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LILRB3
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 326414
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LILRB3
Gene Accession No. P97484
Gene Alias CD85 antigen-like family member A; CD85A; Cell-surface glycoprotein p91; Gp91; HL9; ILT5; ILT-5; immunoglobulin-like transcript 5; leucocyte Ig-like receptor B3; leukocyte immunoglobulin like receptor B3; leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; LILRA6; Lilrb3; LIR3; LIR-3; monocyte inhibitory receptor HL9; paired Ig-like receptor B; paired immunoglobulin-like receptor B; PIRB; PIR-B
Gene Symbols LILRB3
Host Species Rat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse PIR-B Gly24-Gly635.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18733
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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