Invitrogen™ Pirh2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556442

Catalog No. PIPA556442

Description

Immunogen sequence: CDICHLFDKD KKQYHCENCG ICRIGPKEDF FHCLKCNLCL AMNLQGRHKC IENVSRQNCP ICLEDIHTSR VVAHVLPCGH L Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 94%.

The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Pirh2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RCHY1
• Gene Alias: Androgen receptor N-terminal-interacting protein; androgen-receptor N-terminal-interacting protein; ARNIP; Chimp; CH-rich interacting match with PLAG1; CH-rich-interacting match with PLAG1; DKFZp586C1620; E3 ubiquitin-protein ligase Pirh2; h PRO1996; hPirh2; p53-induced protein with a RING-H2 domain; p53-induced RING-H2 protein; PIRH2; PIRH2E; PIRH2F; PRO1996; RCHY1; ring finger and CHY zinc finger domain containing 1; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; Zfp363; Zinc finger protein 363; zinc finger, CHY-type; Znf363
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25898
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96PM5
• Gene Symbols: RCHY1
• Immunogen: Recombinant protein corresponding to Human Pirh2. Recombinant protein control fragment (Product #RP-95489).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG