Invitrogen™ Pirh2 Recombinant Rabbit Monoclonal Antibody (4Q5H9)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537910

Catalog No. PIMA537910

Description

Positive Samples: HCT116 Immunogen sequence: HVLPCGHLLH RTCYEEMLKE GYRCPLCMHS ALDMTRYWRQ LDDEVAQTPM PSEYQNMTVD ILCNDCNGRS TVQFHILGMK CKICESYNTA QAGGRRISLD QQ.

The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Pirh2
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96PM5, Q9CR50
• Gene Symbols: RCHY1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-261 of human RCHY1 (Q96PM5).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 4Q5H9
• Conjugate: Unconjugated
• Gene: RCHY1
• Gene Alias: Androgen receptor N-terminal-interacting protein; androgen-receptor N-terminal-interacting protein; ARNIP; Chimp; CH-rich interacting match with PLAG1; CH-rich-interacting match with PLAG1; DKFZp586C1620; E3 ubiquitin-protein ligase Pirh2; h PRO1996; hPirh2; p53-induced protein with a RING-H2 domain; p53-induced RING-H2 protein; PIRH2; PIRH2E; PIRH2F; PRO1996; RCHY1; ring finger and CHY zinc finger domain containing 1; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; Zfp363; Zinc finger protein 363; zinc finger, CHY-type; Znf363
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25898, 68098
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov