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Invitrogen™ PIST Polyclonal Antibody
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Catalog No. PIPA518240
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100 μg
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Catalog No. Quantity
PIPA518240 100 μg
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Catalog No. PIPA518240 Supplier Invitrogen™ Supplier No. PA518240
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIST
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene GOPC
Gene Accession No. Q9HD26
Gene Alias 2210402P09Rik; AI844555; CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; Fused in glioblastoma; golgi associated PDZ and coiled-coil motif containing; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; Gopc; GOPC1; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST
Gene Symbols GOPC
Host Species Goat
Immunogen Synthetic peptide sequence (LDDLHTLYHKKSY) corresponding to the C-terminus amino acids of GOPC (aa 450-462).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57120
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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