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Invitrogen™ PIST Recombinant Rabbit Monoclonal Antibody (JG79-35)
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Catalog No. PIMA534771
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100 μL
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PIMA534771 100 μL
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Catalog No. PIMA534771 Supplier Invitrogen™ Supplier No. MA534771
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: SiHa, HepG2, MCF-7, SKOV-3, human liver cancer tissue, human colon tissue, human kidney tissue, mouse brain tissue.

PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIST
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JG79-35
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene GOPC
Gene Accession No. Q9HD26
Gene Alias 2210402P09Rik; AI844555; CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; Fused in glioblastoma; golgi associated PDZ and coiled-coil motif containing; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; Gopc; GOPC1; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST
Gene Symbols GOPC
Host Species Rabbit
Immunogen Recombinant protein within Human PIST aa 1-140.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57120
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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