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Invitrogen™ PIT1 Polyclonal Antibody
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Catalog No. PIPA584020
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100 μL
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PIPA584020 100 μL
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Catalog No. PIPA584020 Supplier Invitrogen™ Supplier No. PA584020
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FPDHTLSHGF PPIHQPLLAE DPTAADFKQE LRRKSKLVEE PIDMDSPEIR ELEKFANEFK VRRIKLGYTQ TNVGEALAAV HGS Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 94%.

PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
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Specifications

Antigen PIT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POU1F1
Gene Accession No. P28069
Gene Alias CPHD1; dw; dwarf; GHF1; GHF-1; GHF1A; growth hormone factor 1; Hmp1; homeodomain protein for Growth Hormone (GH); PIT1; pit-1; Pit1-rs1; PIT1Z; Pituary specific transcription factor 1 (growth hormone factor 1); pituitary specific transcription factor 1; pituitary specific transcription factor 1, related sequence 1; pituitary-specific positive transcription factor 1; pituitary-specific positive transcription factor 1 variant w; POU class 1 homeobox 1; POU domain, class 1, transcription factor 1; POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1); POU1F1; POU1F1a; transcription factor Pit-1
Gene Symbols POU1F1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POU1F1. Recombinant protein control fragment (Product #RP-106298).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5449
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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