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PITX2 Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993320
Encompass
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50-199-3320 10 μL
50-199-3319 100 μL
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Catalog No. 50-199-3320 Supplier Active Motif Supplier No. 61304
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Rabbit Polyclonal Antibody

Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

Specifications

Antigen PITX2
Applications Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene PITX2
Gene Accession No. Q99697
Gene Alias 9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; ARP1; BOS_6374; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; Orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; Paired-like homeodomain transcription factor 2; Paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; PITX2; Pitx-2; Pitx2c; Ptx2; RGS; RIEG; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S a 1 glycoprotein; S a1glycoprotein; Solurshin
Gene Symbols PITX2
Host Species Rabbit
Immunogen This PITX2 antibody was raised against a peptide within the N-terminal region of human PITX2.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5308
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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