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Invitrogen™ PITX2 Recombinant Rabbit Monoclonal Antibody (6X1W3)
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Catalog No. FEMA551267
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FEMA551267 100 μL
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Catalog No. FEMA551267 Supplier Invitrogen™ Supplier No. MA551267
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: METNCRKLVS ACVQLGVQPA AVECLFSKDS EIKKVEFTDS PESRKEAASS KFFPRQHPGA NEKDKSQQGK NEDVGAEDPS KKKRQRRQRT HFTSQQLQEL.

Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PITX2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 6X1W3
Concentration 0.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene PITX2
Gene Accession No. Q99697
Gene Alias 9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; Arp1; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired like homeodomain transcription factor 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; paired-like homeodomain transcription factor 2; paired-like homeodomain transcription factor 2c; paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; Pitx2; Pitx-2; Pitx2c; Ptx2; Rgs; Rieg; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S α 1 glycoprotein; S α1glycoprotein; Solurshin
Gene Symbols PITX2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Pituitary homeobox 2 (PITX2) (NP_700475.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5308
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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