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Invitrogen™ PKA beta Monoclonal Antibody (2G8-1D12)
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Catalog No. PIMA519698
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100 μg
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Catalog No. Quantity
PIMA519698 100 μg
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Catalog No. PIMA519698 Supplier Invitrogen™ Supplier No. MA519698
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Mouse Monoclonal Antibody

Peptide Sequence: MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL GTGSFGRVML VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKNF.

The catalytic subunit C-beta of PKA (PRKACB) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1. PRKACB is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKA beta
Applications ELISA
Classification Monoclonal
Clone 2G8-1D12
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene PRKACB
Gene Accession No. P22694
Gene Alias cAMP-dependent protein kinase C beta; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; Pkacb; PRKACB; protein kinase A catalytic subunit beta; protein kinase cAMP-activated catalytic subunit beta; protein kinase, cAMP dependent, catalytic, beta; protein kinase, cAMP-dependent, beta catalytic subunit; protein kinase, cAMP-dependent, catalytic, beta
Gene Symbols PRKACB
Host Species Mouse
Immunogen PRKACB (AAH16285, 1 a.a. ~ 257 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5567
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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