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Invitrogen™ PKA beta Polyclonal Antibody
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Catalog No. PIPA583105
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100 μL
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PIPA583105 100 μL
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Catalog No. PIPA583105 Supplier Invitrogen™ Supplier No. PA583105
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAAYREPPCN QYTGTTTALQ KLEGFASRLF HRHSKGTAHD QKTALENDSL HFSEHTALWD RSMKEFLAKA KEDFLKKWEN PTQNNAGLED FER Highest antigen sequence indentity to the following orthologs: Mouse - 73%, Rat - 29%.

The catalytic subunit C-beta of PKA (PRKACB) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1. PRKACB is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKA beta
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PRKACB
Gene Accession No. P22694
Gene Alias cAMP-dependent protein kinase C beta; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; Pkacb; PRKACB; protein kinase A catalytic subunit beta; protein kinase cAMP-activated catalytic subunit beta; protein kinase, cAMP dependent, catalytic, beta; protein kinase, cAMP-dependent, beta catalytic subunit; protein kinase, cAMP-dependent, catalytic, beta
Gene Symbols PRKACB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PRKACB. Recombinant protein control fragment (Product #RP-102341).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5567
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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