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Invitrogen™ PKC epsilon Recombinant Rabbit Monoclonal Antibody (8I8K4)
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Catalog No. PIMA535617
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100 μL
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PIMA535617 100 μL
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Catalog No. PIMA535617 Supplier Invitrogen™ Supplier No. MA535617
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: RSRKFDEPRS RFYAAEVTSA LMFLHQHGVI YRDLKLDNIL LDAEGHCKLA DFGMCKEGIL NGVTTTTFCG TPDYIAPEIL QELEYGPSVD WWALGVLMYE M.

The PKC family of serine/threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKC epsilon
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 8I8K4
Concentration 0.94 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PRKCE
Gene Accession No. P16054
Gene Alias 5830406C15Rik; MGC125656; MGC125657; nPKC-epsilon; PKC e; PKC[e]; Pkce; Pkcea; PKCepsilon; PRKCE; PRKCH; protein kinase C; protein kinase C epsilon; protein kinase C epsilon type; protein kinase C, epsilon; protein kinase C, eta; R75156
Gene Symbols PRKCE
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 500-600 of human PKC epsilon (Q02156).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18754
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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