Invitrogen™ PKC mu Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578126

Catalog No. PIPA578126

Description

Positive Control: NIH-3T3 Predicted reactivity: Mouse (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.

Specifications

• Antigen: PKC mu
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Prkd3
• Gene Alias: 4930557O20Rik; 5730497N19Rik; AI325941; DKFZP586E0820; EPK2; HSPC187; nPKC-D1; nPKC-D2; nPKC-mu; nPKC-nu; PKC mu; PKC nu; PKC u; PKC v; Pkcm; PKCmu; PKC-MU; Pkcnu; PKC-NU; PKCu; PKC-u; PKCv; PKC-v; Pkd; PKD1; PKD2; PKD3; Prkcm; PRKCN; Prkd1; PRKD2; PRKD3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D2; protein kinase D3; protein kinase EPK2; RGD1308054; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D2; Serine/threonine-protein kinase D3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101540, 18760, 23683, 25865, 5587, 75292
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.93 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O94806, Q15139, Q62101, Q8BZ03, Q8K1Y2, Q9BZL6
• Gene Symbols: PRKD1, Prkd2, Prkd3
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse PKC mu. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG