PKM (phospho S37) Rabbit anti-Human, Polyclonal , Abnova™

Catalog No.	Quantity
89-956-780	100 μL

Catalog No. 89-956-780 Supplier Abnova Corporation Supplier No. PAB29620

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human PKM.

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]

Specifications

• Antigen: PKM (phospho S37)
• Applications: Immunofluorescence, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human PKM.
• Dilution: Immunofluorescence (1:100-1:200) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: CTHBP/MGC3932/OIP3/PK3/PKM/TCB/THBP1
• Gene Symbols: PKM2
• Host Species: Rabbit
• Immunogen: A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S37 of human PKM.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5315
• Test Specificity: PKM (phospho S37) polyclonal antibody detects endogenous level of PKM only when phosphorylated at serine 37.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid