PKM (phospho S37) Rabbit anti-Human, Polyclonal , Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human PKM.

Supplier:  Abnova Corporation PAB29620

Catalog No. 89-956-780

Description

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]

Specifications

• Antigen: PKM (phospho S37)
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human PKM.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Symbols: PKM2
• Immunogen: A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S37 of human PKM.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: PKM (phospho S37) polyclonal antibody detects endogenous level of PKM only when phosphorylated at serine 37.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:100-1:200) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene Alias: CTHBP/MGC3932/OIP3/PK3/PKM/TCB/THBP1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5315
• Target Species: Human
• Form: Liquid