Invitrogen™ PKM2 Monoclonal Antibody (J.473.9)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA514890

Catalog No. PIMA514890

Description

It is not recommended to aliquot this antibody.

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.

Specifications

• Antigen: PKM2
• Classification: Monoclonal
• Concentration: 5 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P11980, P14618, P52480
• Gene Symbols: PKM
• Immunogen: Synthetic peptide corresponding to the sequence around Gly200 of human PKM2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: J.473.9
• Conjugate: Unconjugated
• Gene: PKM
• Gene Alias: AA414905; AL024370; AL024424; ATP:pyruvate 2-o-phosphotransferase; CTHBP; Cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; HEL-S-30; isozymes M1/M2; m2pk; muscle pyruvate kinase; OIP3; OIP-3; OPA-interacting protein 3; p58; PK, muscle type; PK2; Pk-2; Pk3; Pk-3; PKLR; PKM; pkm.L; PKM12; PKM2; Pykm; pyruvate kinase; pyruvate kinase 2/3; pyruvate kinase 3; pyruvate kinase isozymes M1/M2; pyruvate kinase M1/2; pyruvate kinase M1/2 L homeolog; pyruvate kinase M1/2 L homeolog; pyruvate kinase, muscle; pyruvate kinase muscle isozyme; Pyruvate kinase PKM; pyruvate kinase, liver and RBC; pyruvate kinase, muscle; TCB; THBP1; thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; tu; tumor M2-PK; XELAEV_18018020mg
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18746, 25630, 5315
• Content And Storage: -20°C
• Form: Liquid