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Invitrogen™ PKM2 Polyclonal Antibody
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Catalog No. PIPA5114116
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PIPA5114116 100 μL
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Catalog No. PIPA5114116 Supplier Invitrogen™ Supplier No. PA5114116
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSKPHSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSPPI TARNTGIICT For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%.

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKM2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PKM
Gene Accession No. P14618
Gene Alias AA414905; AL024370; AL024424; ATP:pyruvate 2-o-phosphotransferase; CTHBP; Cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; HEL-S-30; isozymes M1/M2; m2pk; muscle pyruvate kinase; OIP3; OIP-3; OPA-interacting protein 3; p58; PK, muscle type; PK2; Pk-2; Pk3; Pk-3; PKLR; PKM; pkm.L; PKM12; PKM2; Pykm; pyruvate kinase; pyruvate kinase 2/3; pyruvate kinase 3; pyruvate kinase isozymes M1/M2; pyruvate kinase M1/2; pyruvate kinase M1/2 L homeolog; pyruvate kinase M1/2 L homeolog; pyruvate kinase, muscle; pyruvate kinase muscle isozyme; Pyruvate kinase PKM; pyruvate kinase, liver and RBC; pyruvate kinase, muscle; TCB; THBP1; thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; tu; tumor M2-PK; XELAEV_18018020mg
Gene Symbols PKM
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human PKM2 (aa 1-50).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5315
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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