Invitrogen™ PKMYT1 Monoclonal Antibody (2A3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA520597

Catalog No. PIMA520597

Description

Peptide Sequence: PASWLQPLGP PATPPGSPPC SLLLDSSLSS NWDDDSLGPS LSPEAVLART VGSTSTPRSR CTPRDALDLS DINSEPPRGS FPSFEPRNLL SLFEDTLDPT.

PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.

Specifications

• Antigen: PKMYT1
• Classification: Monoclonal
• Concentration: 0.46 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q99640
• Gene Symbols: Pkmyt1
• Immunogen: PKMYT1 (NP_004194.3, 400 a.a. ~ 499 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Proximity Ligation Assay, Western Blot
• Clone: 2A3
• Conjugate: Unconjugated
• Gene: Pkmyt1
• Gene Alias: 6230424P17; AW209059; Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase; Myt1; Myt1 kinase; Pkmyt1; pkmyt1.S; PPP1R126; protein kinase, membrane associated tyrosine/threonine 1; protein kinase, membrane associated tyrosine/threonine 1 S homeolog; protein phosphatase 1, regulatory subunit 126; RGD1305434; XELAEV_18047881mg
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9088
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid