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Invitrogen™ PKN1 Monoclonal Antibody (1B10)
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Catalog No. PIMA519703
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100 μg
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Catalog No. Quantity
PIMA519703 100 μg
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Catalog No. PIMA519703 Supplier Invitrogen™ Supplier No. MA519703
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Description

Mouse Monoclonal Antibody

Peptide Sequence: LDMEPQGCLV AEVTFRNPVI ERIPRLRRQK KIFSKQQGKA FQRARQMNID VATWVRLLRR LIPNATGTGT FSPGASPGSE ARTTGDISVE KLNLGTDSDS SPQKSSRDPP SSPSSLSSPI QESTAPELPS ETQETPGPAL CSPLRKSPLT LEDF.

PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can also be activated by phospholipids. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKN1
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1B10
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene PKN1
Gene Accession No. Q16512
Gene Alias DBK; F730027O18Rik; PAK1; PAK-1; PKN; PKN1; PKN-ALPHA; PRK1; Prkcl1; Protease-activated kinase 1; protein kinase C-like 1; Protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; serine/threonine kinase 3; serine/threonine protein kinase N; serine/threonine-protein kinase N1; serine-threonine kinase N; serine-threonine protein kinase N; Stk3
Gene Symbols PKN1
Host Species Mouse
Immunogen PKN1 (AAH40061, 462 a.a. ~ 615 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5585
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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