PKN1 Mouse anti-Human, Clone:4H10B1, Abnova™

Catalog No.	Quantity
89-333-130	100 μg

Catalog No. 89-333-130 Supplier Abnova Corporation Supplier No. MAB16638

Description

Mouse monoclonal antibody raised against recombinant human PKN1.

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Specifications

• Antigen: PKN1
• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 4H10B1
• Conjugate: Unconjugated
• Description: protein kinase N1
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: PKN1
• Gene Alias: DBK, MGC46204, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 442-620 of human PKN1 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 5585
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b