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Invitrogen™ PKP2 Monoclonal Antibody (8H6)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA518081
Description
This target has a predicted molecular weight of 97 kDa.
Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.
Specifications
PKP2 | |
Monoclonal | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
Q99959 | |
PKP2 | |
Recombinant fragment, corresponding to amino acids 1-350 of Human Plakophilin 2 fused to maltose binding protein. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG1 |
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
8H6 | |
Unconjugated | |
PKP2 | |
1200008D14Rik; 1200012P04Rik; AA516617; ARVD9; PKP2; Pkp2l; plakophilin 2; plakophilin-2 | |
Mouse | |
Protein A | |
RUO | |
5318, 67451 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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