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Invitrogen™ PKP2 Monoclonal Antibody (8H6)
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Catalog No. PIMA518081
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100 μL
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Catalog No. Quantity
PIMA518081 100 μL
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Catalog No. PIMA518081 Supplier Invitrogen™ Supplier No. MA518081
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Mouse Monoclonal Antibody

This target has a predicted molecular weight of 97 kDa.

Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKP2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 8H6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene PKP2
Gene Accession No. Q99959
Gene Alias 1200008D14Rik; 1200012P04Rik; AA516617; ARVD9; PKP2; Pkp2l; plakophilin 2; plakophilin-2
Gene Symbols PKP2
Host Species Mouse
Immunogen Recombinant fragment, corresponding to amino acids 1-350 of Human Plakophilin 2 fused to maltose binding protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5318, 67451
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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