Invitrogen™ PKP3 Monoclonal Antibody (7F6)

Catalog No.	Quantity
PIMA518080	100 μL

Catalog No. PIMA518080 Supplier Invitrogen™ Supplier No. MA518080

Description

Mouse Monoclonal Antibody

This target has a predicted molecular weight of 87 kDa.

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.

Specifications

• Antigen: PKP3
• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 7F6
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: PKP3
• Gene Accession No.: Q9QY23, Q9Y446
• Gene Alias: 2310056L12Rik; Pkp3; plakophilin 3; plakophilin 3b; plakophilin-3
• Gene Symbols: PKP3
• Host Species: Mouse
• Immunogen: Recombinant fragment corresponding to amino acids 1-308 of Human Plakophilin 3 fused to maltose binding protein.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11187, 56460
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1