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Invitrogen™ PKP3 Polyclonal Antibody
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Catalog No. PIPA5103059
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100 μL
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PIPA5103059 100 μL
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Catalog No. PIPA5103059 Supplier Invitrogen™ Supplier No. PA5103059
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PKP3.

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKP3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PKP3
Gene Accession No. Q9QY23, Q9Y446
Gene Alias 2310056L12Rik; Pkp3; plakophilin 3; plakophilin 3b; plakophilin-3
Gene Symbols PKP3
Host Species Rabbit
Immunogen A synthesized peptide derived from human PKP3(Accession Q9Y446), corresponding to amino acid residues R737-K787.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11187, 56460
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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