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Invitrogen™ PLA2G2A Polyclonal Antibody
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Catalog No. PIPA547729
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100 μg
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PIPA547729 100 μg
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Catalog No. PIPA547729 Supplier Invitrogen™ Supplier No. PA547729
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Description

Sheep Polyclonal Antibody

In Western blots, approximately 60% cross-reactivity with recombinant mouse PLA2G2A is observed and less than 5% cross-reactivity with recombinant human (rh) PLA2G1B and rhPLA2G7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLA2G2A
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene PLA2G2A
Gene Accession No. P14555
Gene Alias EC 3.1.1.4; EF; Enhancing factor; eted enzyme type IIA phospholipase A2; GIIC sPLA2; Group IIA phospholipase A2; modifier of Min1; Mom1; non-pancreatic secreted type II phospholipase A2; non-pancreatic secretory phospholipase A2; NPS-PLA2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2 group IIA; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; Pla2; PLA2B; PLA2BPLA2; PLA2G2A; PLA2L; PLA2LPLA2S; PLA2S; PLAS1; platelet phospholipase A2; RASF-A; secretory group II phospholipase A2; sPLA2; sPla2-IIA
Gene Symbols PLA2G2A
Host Species Sheep
Immunogen Sf 21-derived recombinant human PLA2G2A Asn21-Cys144.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5320
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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