Invitrogen™ PLA2G2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110176

Catalog No. PIPA5110176

Description

Immunogen sequence: NLVNFHRMIK LTTGKEAALS YGFYGCHCGV GGRGSPKDAT DRCCVTHDCC YKRLEKRGCG TKFLSYKFSN SGSRITCAKQ DSCRSQLCEC DKAAATCFAR NKTTYNKKYQ YYSNKHCRGS TPRC.

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Specifications

• Antigen: PLA2G2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLA2G2A
• Gene Alias: EC 3.1.1.4; EF; Enhancing factor; eted enzyme type IIA phospholipase A2; GIIC sPLA2; Group IIA phospholipase A2; modifier of Min1; Mom1; non-pancreatic secreted type II phospholipase A2; non-pancreatic secretory phospholipase A2; NPS-PLA2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2 group IIA; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; Pla2; PLA2B; PLA2BPLA2; PLA2G2A; PLA2L; PLA2LPLA2S; PLA2S; PLAS1; platelet phospholipase A2; RASF-A; secretory group II phospholipase A2; sPLA2; sPla2-IIA
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5320
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.28 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P14555
• Gene Symbols: PLA2G2A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-144 of human PLA2G2A (NP_001155201.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG