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PLA2G4A/cPLA2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501569803
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50-156-9803 20 μL
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Catalog No. 50-156-9803 Supplier Bethyl Laboratories, Inc Supplier No. A305205AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Specifications

Antigen PLA2G4A/cPLA2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PLA2G4A
Gene Accession No. P47712
Gene Alias cPLA2; calcium-dependent phospholipid-binding protein; cytosolic phospholipase A2; lysophospholipase; phosphatidylcholine 2-acylhydrolase; phospholipase A2 group IVA
Gene Symbols PLA2G4A
Host Species Rabbit
Immunogen Between 699 and 749
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5321
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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