Invitrogen™ PLA2G4A Monoclonal Antibody (C19)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA541580

Catalog No. PIMA541580

Description

PLA2G4A Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Specifications

• Antigen: PLA2G4A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P47712
• Gene Symbols: PLA2G4A
• Immunogen: Recombinant protein Cytosolic Phospholipase A2. The antigen corresponds to amino acid range 1-178 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: C19
• Conjugate: Unconjugated
• Gene: PLA2G4A
• Gene Alias: calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 5321
• Content And Storage: -20°C
• Form: Liquid