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Invitrogen™ PLA2G4A Monoclonal Antibody (C19)

Catalog No. PIMA543625
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200 μL
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PIMA543625 20 μL
PIMA541580 200 μL
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Catalog No. PIMA543625 Supplier Invitrogen™ Supplier No. MA543625
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Description

Mouse Monoclonal Antibody

PLA2G4A Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLA2G4A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone C19
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene PLA2G4A
Gene Accession No. P47712
Gene Alias calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A
Gene Symbols PLA2G4A
Host Species Mouse
Immunogen Recombinant protein Cytosolic Phospholipase A2. The antigen corresponds to amino acid range 1-178 of the target protein.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5321
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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