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Invitrogen™ PLA2G4A Polyclonal Antibody
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Catalog No. PIPA5111304
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100 μL
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PIPA5111304 100 μL
PIPA5111389 100 μL
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Catalog No. PIPA5111304 Supplier Invitrogen™ Supplier No. PA5111304
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PRETEEEKEI ADFDIFDDPE SPFSTFNFQY PNQAFKRLHD LMHFNTLNNI DVIKEAMVES IEYRRQNPSR CSVSLSNVEA RRFFNKEFLS K Highest antigen sequence indentity to the following orthologs: Rat - 93%, Mouse - 93%.

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLA2G4A
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PLA2G4A
Gene Accession No. P47712
Gene Alias calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A
Gene Symbols PLA2G4A
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human PLA2G4A. Recombinant protein control fragment (Product #RP-103063).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5321
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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