PLA2R1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA587610

Catalog No. PIPA587610

Description

Immunogen sequence: GASWWIGLQE ERANDEFRWR DGTPVIYQNW DTGRERTVNN QSQRCGFISS ITGLWGSEEC SVSMPSICKR KKVWLIEKKK DTPKQHGTCP KGWLYFNYKC LLLNIPKDPS SWKNWTHAQH FCAEEGGTLV AIESEVEQAF ITMNLFGQTT SVWIGLQNDD YETWLNGKPV VYSNWSPFDI INIPSHNTTE VQKHIPLCAL LSSNPNFHFT GKWYFEDCGK EGYGFVCEKM QDTSGHGVNT SDMYPMPNTL EYGNRTYKII N; Positive Samples: 293T, SH-SY5Y, Mouse liver, Mouse heart; Cellular Location: Cell membrane, Single-pass type I membrane protein

This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: PLA2R1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLA2R1
• Gene Symbols: Pla2r1
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot
• Concentration: 3.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13018, Q62028
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18779, 22925, 295631
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid