Invitrogen™ PLAC4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521047

Catalog No. PIPA521047

Description

A suggested positive control is human placenta lysate. PA5-21047 can be used with blocking peptide PEP-1161.

PLAC4 (placenta-specific protein 4), was initially discovered as a gene whose mRNA was expressed in placental syncytiotrophoblast and choriocarcinoma cells. While the function of PLAC4 is currently unclear, its gene is known to be located on chromosome 21q22.3. Due to the PLAC4 gene location on chromosome 21 and the release of its mRNA transcripts into maternal bloodstream from the placenta, it has been proposed to be a useful marker noninvasive prenatal chromosome 21 aneuploidy detection, although other reports suggests that PLAC4 mRNA levels are not altered in the maternal circulation of pregnancies with trisomy 21.

Specifications

• Antigen: PLAC4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLAC4
• Gene Alias: C21orf115; PLAC4; placenta specific 4; placenta-specific 4; placenta-specific protein 4; PRED78
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 191585
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8WY50
• Gene Symbols: PLAC4
• Immunogen: A 17 amino acid peptide near the center of human PLAC4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG