Invitrogen™ PLAGL1 Monoclonal Antibody (8D8C5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531853

Catalog No. PIMA531853

Description

MA5-31853 has been tested in indirect ELISA.

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.

Specifications

• Antigen: PLAGL1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q9UM63
• Gene Symbols: Plagl1
• Immunogen: Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 8D8C5
• Conjugate: Unconjugated
• Gene: Plagl1
• Gene Alias: Lost on transformation 1; LOT1; LOT-1; PLAG1 like zinc finger 1; PLAGL1; PLAG-like 1; pleiomorphic adenoma gene-like 1; Pleiomorphic adenoma-like protein 1; Tumor suppressor ZAC; ZAC; Zac1; zinc finger protein PLAGL1; zinc finger protein regulator of apoptosis and cell cycle arrest; zinc finger protein Zac 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5325
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid