Invitrogen™ PLAGL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565970

Catalog No. PIPA565970

Description

Immunogen sequence: QELMKESLQTG DLLSTFHTIS PSFQLKAAAL PPFPLGASAQ NGLASSLPAE VHSLTLSPPE QAAQPMQPLP ESLASLHPSV SPGSP Highest antigen sequence identity to the following orthologs - mouse 50%, rat 47%.

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.

Specifications

• Antigen: PLAGL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Plagl1
• Gene Alias: Lost on transformation 1; LOT1; LOT-1; PLAG1 like zinc finger 1; PLAGL1; PLAG-like 1; pleiomorphic adenoma gene-like 1; Pleiomorphic adenoma-like protein 1; Tumor suppressor ZAC; ZAC; Zac1; zinc finger protein PLAGL1; zinc finger protein regulator of apoptosis and cell cycle arrest; zinc finger protein Zac 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5325
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UM63
• Gene Symbols: Plagl1
• Immunogen: Recombinant Human PLAGL1. Recombinant protein control fragment (Product #RP-105023).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov