Plakophilin 1 Antibody (10B2), Alexa Fluor™ 532, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254526AF532

Catalog No. NP2426A32

Description

Plakophilin 1 Monoclonal specifically detects Plakophilin 1 in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: Plakophilin 1
• Classification: Monoclonal
• Conjugate: Alexa Fluor 532
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: PKP1
• Immunogen: N-terminus of human Plakophilin 1 protein (Uniprot: Q13835)
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: 10B2
• Dilution: Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
• Gene Alias: B6PBand 6 protein, MGC138829, plakophilin 1 (ectodermal dysplasia/skin fragility syndrome), plakophilin-1
• Host Species: Mouse
• Quantity: 0.1 mL
• Gene ID (Entrez): 5317
• Target Species: Human, Mouse
• Isotype: IgG1 κ