Plakophilin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-2123	Proteintech Group Inc 183381AP150UL	150 μL

Description

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ∽87 kDa.

Specifications

• Antigen: Plakophilin 3
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q9QY23, Q9Y446
• Gene ID (Entrez): 11187, 293619, 56460
• Immunogen: Plakophilin 3 Fusion Protein Ag13062
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PKP3

• Concentration: 0.2 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: PKP3, plakophilin 3
• Gene Symbols: Pkp3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody