Plasma Cell Antibody (LIV3G11 (7B18)), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP225239	Novus Biologicals NBP225239	0.1 mg

Description

Plasma Cell Monoclonal specifically detects Plasma Cell in Human, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Plasma Cell
• Concentration: 0.2 mg/ml
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Immunology
• Gene Alias: Plasma
• Isotype: IgG2a κ
• Purification Method: Protein A or G purified
• Test Specificity: It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This monoclonal antibody superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this monoclonal antibody is not suitable for staining frozen tissues.

• Clone: LIV3G11 (7B18)
• Dilution: Immunohistochemistry-Paraffin 0.5-1ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Rat (Negative)
• Immunogen: Pancreatic cancer related serum mucin was used as the immunogen for the Plasma Cell antibody.
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

For Research Use Only